Associate Research Scientist - Protein Purification

Company: Thermo Fisher Scientific Inc.
Location: Rockville
Posted on: May 29, 2023

Job Description:

Job DescriptionDescription - ExternalAt Thermo Fisher Scientific, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on - now and in the future.Location/Division Specific InformationLocation: Rockville, MDWithin our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to demonstrate the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.A day in the Life:The Associate Research Scientist in this role would be responsible for implementing and optimizing experimental protocols in the areas of protein purification and analytics. - -Prior experience in -recombinant protein purification from mammalian and/or bacterial expression systems using AKTA FPLC systems is required. -Hands on experience with high throughput purification, protein expression, tangential flow filtration or HPLC systems would be an added advantage.Key Responsibilities

• Carefully executes and documents experiments/technical studies/tasks with minimal supervision, maintaining good scientific practice.
• Participates in experimental planning by applying critical thinking, experience and scientific knowledge to the data analysis.
• Interprets results and communicates to his/her supervisor.
• Operates and maintains designated lab equipment and trains others as needed.
• Participates in project meetings, contributes detailed oral or written summaries of results.
• Assist SED workstream leaders and technical teams to coordinate and facilitate project deliverables by:
• Scheduling CMC matrix/workstream/technical meetings
• Preparing meeting agenda
• Issuing minutes, tracking decisions and action items
• Following up on action items to ensure completion through collaboration with SMEs
• Project resource planning and reporting of project forecasts and actuals through internal planning systems (i.e. IRM, ET, Spotfire dashboards)
• Maintain detailed CMC dashboard to support SED visibility into program timelines, deliverables and risk profiles
• Manage OneNote as source for project information
• Track detailed technical deliverables and provide outlook on future deliverables
• Track submission source documents, including data verification and upload into VQD
• Manage the submission of shipping requests, collate appropriate documentation to support shipments and track R&D shipments of samples, CTM and other time sensitive materials
• Communicate with key business partners (internal and external) to ensure accurate and up to date information is maintained for program delivery
• Provide regular (weekly/biweekly) project communications with Clin Ops regarding key clinically meaningful data (CoA's stability updates etc.)
• Liaise with SED Business Operations to ensure purchase orders and invoices are up to date.Qualifications - ExternalEducationBachelor's degree in a Science related field or equivalent and relevant formal academic / vocational qualificationPrevious experience that provides the knowledge, skills, and abilities to perform the job (comparable to 6 to 8 years') or equivalent combination of education, training, & experience.Knowledge, Skills, Abilities
  • Ability to perform basic to moderately complex laboratory activities.
  • Fundamental understanding of principles and applications of protein biochemistry, and demonstrated ability in protein purification, western blot and protein quantitation are required.
  • Training in areas such as protein and DNA extraction / quantification is an added advantage.
  • Use of analytical tools, other pharmaceutical analysis and validation techniques, and/ or experience with analytical development is highly desirable.
  • Good attention to detail
  • Ability to utilize Microsoft Excel, Word and PowerPoint to perform tasks
  • Good written and oral communication skills
  • Time management skills
  • Problem solving and troubleshooting abilities
  • Ability to work in a collaborative work environment with a teamPhysical Requirements / Work Environment -Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below are the working environment/requirements for this role:
    • Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
    • Able to work upright and stationary and/or standing for typical working hours.
    • Able to lift and move objects up to 25 pounds.
    • Able to work in non-traditional work environments.
    • Able to use and learn standard office equipment and technology with proficiency.
    • May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
    • Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
    • As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.

Keywords: Thermo Fisher Scientific Inc., Rockville , Associate Research Scientist - Protein Purification, Other , Rockville, Maryland