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Expert Scientist, Computational Biology

Company: GlaxoSmithKline
Location: Rockville
Posted on: September 19, 2022

Job Description:

Site Name: USA - Maryland - RockvillePosted Date: Mar 2 2022Are you interested in making significant contributions to vaccines R&D through the integration and analysis of complex, high dimensional data sets? -Do you want to impact global health by applying your expertise to the development of the next generation of vaccines? If so, GSK's Data Sciences and Computational Vaccinology team in Rockville, Maryland is looking for an Expert scientist Computational Biology and this role could be ideal for you.As an Expert scientist Computational Biology, you will be responsible for the analysis and integration of systems vaccinology data from clinical and preclinical studies to elucidate the mechanism of action of our vaccine platforms, such as, RNA vaccines. The results will be used to drive discussions on platform improvements, vaccine efficacy, and safety. You will ensure that data analytics and bioinformatics deliverables for Vaccines R&D projects are the top of industry standards with respect to scientific excellence, quality, and timelines.This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

  • Represent Data Sciences and Computational Vaccinology (DSCV) as subject matter expert in cross-functional project teams
  • Provide input to the team scientific strategy, processes, and objectives in alignment with the GSK Vaccines R&D strategy
  • Perform:
    • Bioinformatics/data analytics activities for Vaccines R&D; data and knowledge integration for hypothesis generation; data modeling for innovative immunological assays; high-dimensional readouts; and human and microbial genomics
    • Development of tailored systems and analytical models for explorative analytics of pre-clinical, clinical, and epidemiological data; development of analysis pipelines using combinations of heterogeneous, high dimensional datasets and tools
    • Advise on study design, readout selection and data formats, data analysis strategies
    • Preparation and publication of scientific papers and congress reports
    • Identify and lead initiatives to innovate, foster collaboration, promote the data driven organization, and improve processes.
    • Communicate activities, results, and principles to internal stakeholders and scientific community, translating complex solutions into simple, understandable and effective messages
    • Initiate and lead scientific collaborations with external partnersWhy you?Basic Qualifications: We are looking for professionals with these required skills to achieve our goals:
      • PhD or equivalent work experience in Bioinformatics, Systems Immunology, Computational Biology, Engineering, Data and Computer Science, Statistics, or a similar domain
      • 3+ years of work experience as postdoctoral researcher or equivalent
      • Proficiency / publication record in one or more of the following areas:
        • Bioinformatics and genomics (including single cell genomics) applied to immunological questions and/or vaccinology
        • Systems immunology, vaccinology and immuno-genomics
        • Data mining and machine learning, multivariate biomarkers discovery and validation
        • Data modeling for individual and integrated analysis of innovative immune assays (e.g., high dimensional flow cytometry, systems serology), high-dimensional readouts
        • Experience in programming (R and Python), data analytics, and modeling skillsPreferred Qualifications: If you have the following characteristics, it would be a plus:
          • Good understanding of biological and immunological processes related to vaccination and infectious diseases
          • Good leadership skills in a scientifically oriented environment, i.e., proposing and driving research projects and taking accountability for outcomes
          • Fluent English (spoken and written)
          • Good communication skills, ability to simplify complex problems and communicate complex solutions in a simple and effective manner
          • Good networking skills and fluent interactions with one or more scientific communities
          • Ability to influence performance in a matrix organization through negotiation and communicationWhy GSK?At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in -Consumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggest -changes we've made to our business in over 20 years. -We're on track to separate and create two new companies in 2022: -New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics -science; and a new world-leading consumer healthcare company of loved and trusted brands.------With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of disease -together - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and -as a new GSK where outstanding people thrive.------Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture -that is -ambitious for patients -- so we deliver what matters better and faster; -accountable for impact -- with clear ownership of -goals and support to succeed; and -where we do the right thing. So, if you're ready to improve the lives of billions, join us at this -exciting moment in our journey. Join our challenge to get Ahead Together.---*LI-GSK#VaccinesRDIf you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. -GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.Important notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting site.

Keywords: GlaxoSmithKline, Rockville , Expert Scientist, Computational Biology, Other , Rockville, Maryland

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