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Scientist I - Upstream

Company: Charles River
Location: Rockville
Posted on: August 6, 2022

Job Description:

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.IMPORTANT: In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process. Please make sure work history and education are added correctly. Job Summary The Scientist I, Upstream Process Development is responsible for studying properties of mammalian cell culture, developing new assays, and exploring new methods for viral vector production within the department of Process Development. Duties and Responsibilities --- Work with Process Development scientists and Director to design, plan, and conduct experiments to optimize and better characterize client/internal processes and projects. --- Lead execution of experiments from seed culture generation, data collection and final harvest of bioreactors. --- Sample of bioreactors, analysis, and data collection of current experiments for process development. --- Maintain an up-to-date inventory of all necessary laboratory and bioreactor consumables. --- Perform data analysis, prepare technical reports, write SOPs, and make internal and external presentations. --- Coordinate with Facilities and Engineering department and outside vendors for repair, maintenance, and/or calibration of laboratory equipment and systems. --- Preparation of reagents, media/buffer, and equipment as needed to support experiments. --- Responsible for documenting and organizing experiments according to Good Documentation Practices. --- Maintain good communication and collaboration with colleagues and junior members of team. --- Assistance with or support of manufacturing activities. --- Other responsibilities as needed. Job Qualifications --- Bachelor of Science, Master's Degree, or Ph.D. in Molecular Biology, Chemical Engineering, Biochemical Engineering, Microbiology, or related field --- 0-2 years (Ph.D. level), 2-4 years (M.S. level) or 4-6 years (B.S. level) of relevant experience --- Experience with cell culture of various scales including shaking flasks, WAVE bags, and /or XDR bioreactor vessels--- Must be a team player prepared to work in and embrace a team-based culture --- Proven troubleshooting, technical writing, problem solving and investigational skills --- Ability to think critically and creatively to identify and solve problems --- Proven ability to work independently and to work on multiple projects simultaneously --- Computer skills including Microsoft Office (Outlook and Excel) --- Well-organized and ability to pay attention to detail --- Excellent verbal and written communication skills IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV. Vaccine MandateCharles River is a U.S. Federal Contractor. As a result, we must follow the Presidential Executive Order to mandate vaccinations, and ensure our employees are fully vaccinated against COVID-19. Our main priority is the wellbeing, health, and safety of our people. We require proof of vaccination from all employees. Anyone with requests for disability-related and/or religious exemptions should contact Talent Acquisition (crrecruitment_US@crl.com) so that information can be provided about the accommodation process at Charles River. About Biologics Testing SolutionsWith more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

Keywords: Charles River, Rockville , Scientist I - Upstream, Other , Rockville, Maryland

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